Turned vase with nude almost lost (7)

'lost' is the definition.
('unsaved' can be similar in meaning to 'lost')

'turned vase with nude almost' is the wordplay.
'turned' indicates anagramming the letters.
'with' says to put letters next to each other.
'almost' means to remove the last letter (most of the word but not all of it).
'nude' with its last letter removed is 'nud'.
'vase'+'nud'='vasenud'
'vasenud' with letters rearranged gives 'UNSAVED'.