Turning up at home, getting into bed, is pick-me-up (5)
I believe the answer is:
tonic
'pick-me-up' is the definition.
(thesaurus)
'turning up at home getting into bed' is the wordplay.
'turning up' says the letters should be written backwards.
'at home' becomes 'in' ('in' can be similar in meaning to 'at home').
'getting into' indicates putting letters inside.
'bed' becomes 'cot' (cot is a kind of bed).
'in' going into 'cot' is 'cinot'.
'cinot' back-to-front is 'TONIC'.
'is' acts as a link.
(Other definitions for tonic that I've seen before include "Producing tension of muscles" , "medicinal preparation" , "Restorative that invigorates" , "Keynote of a scale" , "Gin mixer - pick-me-up" .)