Twelve practise meditation, possibly? (5)
I believe the answer is:
dozen
'twelve' is the definition.
(synonyms)
'practise meditation possibly?' is the wordplay.
'practise' becomes 'do' (synonyms).
'meditation possibly?' becomes 'zen' (school of Buddhism with a focus on meditation).
'do'+'zen'='DOZEN'
(Other definitions for dozen that I've seen before include "Set of twelve" , "Twelve (or thirteen for a baker?)" , "Group of 12" , "XII" , "Quantity of e.g. eggs" .)