Twister spoiled a party (7)
I believe the answer is:
tornado
'twister' is the definition.
(term for a tornado)
'spoiled a party' is the wordplay.
'spoiled' becomes 'torn' (tear can mean to spoil or destroy).
'party' becomes 'do' (do is a kind of party).
'torn'+'a'+'do'='TORNADO'
(Other definitions for tornado that I've seen before include "Road not turned in the windstorm" , "Violent wind vortex" , "Type of cyclone" , "A major blow" , "Destructive windstorm" .)