Up there, you're in trouble (5)
I believe the answer is:
creek
'trouble' is the definition.
Although both the answer and definition are singular nouns, I don't understand how they can define each other.
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for creek that I've seen before include "Natural stream" , "Rivulet" , "Narrow waterway" , "Small narrow inlet" , "Narrow inlet from the sea" .)