Vasant designed Guiding system en route (6)
I believe the answer is:
satnav
'guiding system en route' is the definition.
I don't know anything about this answer so I can't tell whether it can be defined by this definition.
'vasant designed' is the wordplay.
'designed' indicates an anagram (designed with the letters).
'vasant' with letters rearranged gives 'SATNAV'.
Can you help me to learn more?
(Other definitions for satnav that I've seen before include "Electronic direction finder" , "Road atlas replacer" , "one may help the driver" , "Modern substitute for a map" , "Talking road map?" .)