Very comfortable partners with extremely lyrical song and dance (4-2-2)
I believe the answer is:
well-to-do
'very comfortable' is the definition.
(I've seen this before)
'partners with extremely lyrical song and dance' is the wordplay.
'partners' becomes 'we' (West and East are partners in the game bridge).
'with' means one lot of letters go next to another.
'extremely' suggests removing the centre (only the extremes of the word are used).
'song and dance' becomes 'to do' (I've seen this before).
'lyrical' with its centre taken out is 'll'.
'we'+'ll'+'todo'='WELL-TO-DO'
(Other definitions for well-to-do that I've seen before include "Rich; old towel (anag.)" , "Fairly rich, prosperous" , "with a lot of funds" , "Quite wealthy" , "Financially comfortable" .)