Vile wolf heartlessly wearing drag in East London… (5)
I believe the answer is:
awful
'vile' is the definition.
(thesaurus)
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for awful that I've seen before include "Not good at all" , "Very poor" , "Dreadful and dire" , "The pits" , "dire result" .)