Voyage lots of sailors talked of (6)
I believe the answer is:
cruise
'voyage' is the definition.
(type of sea voyage)
'lots of sailors talked of' is the wordplay.
'lots of sailors' becomes 'crews' (more than one crew).
'talked of' indicates a 'sounds like' (homophone) clue.
'crews' sounds like 'CRUISE'.
(Other definitions for cruise that I've seen before include "Sail smoothly" , "Sail on a ship" , "Coast" , "Pleasure ocean voyage" , "Pleasure trip on ship" .)