Waste Home Counties salary? (6)
I believe the answer is:
sewage
'waste' is the definition.
(sewage is a kind of waste)
'home counties salary?' is the wordplay.
'home counties' becomes 'SE' (Home Counties in the South East of England).
'salary?' becomes 'wage' (synonyms).
'se'+'wage'='SEWAGE'
(Other definitions for sewage that I've seen before include "Waste matter carried away in drains" , "Liquid waste" , "Waste water, etc" , "Drained waste" , "Waste flowing in pipes" .)