Web user prised off (6)
I believe the answer is:
spider
'web user' is the definition.
(I've seen this in another clue)
'prised off' is the wordplay.
'off' indicates anagramming the letters.
'prised' with letters rearranged gives 'SPIDER'.
(Other definitions for spider that I've seen before include "Prised out the insect" , "Snooker-cue rest" , "Harvester" , "Creepy-crawly" , "Web designer?" .)