When William's in a state, Sean acts (4)
I believe the answer is:
penn
'state sean acts' is the definition.
'penn' can be an answer for 'state' (abbreviation for Pennsylvania). I'm not certain of the 'sean acts' bit.
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for penn that I've seen before include "Early Quaker leader" , "US state (abbrev.)" , "Milk actor" , "founder of colony" , "Colonising Quaker" .)