Wine in Rioja's tiresome (4)
I believe the answer is:
asti
'wine' is the definition.
(I've seen this before)
'in rioja's tiresome' is the wordplay.
'in' indicates the answer is hidden within the clue.
'ASTI' is hidden within 'riojas tiresome'.
(Other definitions for asti that I've seen before include "Sparkling drink" , "Bubbly wine" , "Fizzy wine" , "White wine named after a town in Piedmont" , "Italian wine - (then change a letter for ...)" .)