Wit ran to church more than once (5)
I believe the answer is:
twice
'more than once' is the definition.
(I've seen this in another clue)
'wit ran to church' is the wordplay.
'ran' indicates an anagram (letters have run around).
'to church' becomes 'CE' (Church of England).
'wit' anagrammed gives 'twi'.
'twi'+'ce'='TWICE'
(Other definitions for twice that I've seen before include "You only live -- (film)" , "Double in quantity" , "Doubly" , "Two times" .)