With fortune, take time over gambling game (5)
I believe the answer is:
lotto
'gambling game' is the definition.
(I've seen this before)
'with fortune take time over' is the wordplay.
'with' says to put letters next to each other.
'fortune' becomes 'lot' ('lot' can be a synonym of 'fortune').
'take time over' becomes 'to' (I am not sure about this - if you are sure you should believe this answer much more).
'lot' put next to 'to' is 'LOTTO'.
Can you help me to learn more?
(Other definitions for lotto that I've seen before include "Housey-housey, bingo" , "National gambling game" , "gamble" , "house" , "Venetian painter - gambling game" .)