Work left Tunis, sadly - he will take advantage (11)
I believe the answer is:
opportunist
'he will take advantage' is the definition.
The answer is a person as well as being a singular noun. This is suggested by the definition.
'work left tunis sadly' is the wordplay.
'work' becomes 'op' (common abbreviation for 'opus').
'left' becomes 'port' (left side of a ship - opposite of starboard).
'sadly' indicates an anagram.
'tunis' anagrammed gives 'unist'.
'op'+'port'+'unist'='OPPORTUNIST'
Can you help me to learn more?
(Other definitions for opportunist that I've seen before include "One making most of" , "One taking advantage of changing circumstances" , "Person without fixed principles" , "Chancer" .)