Worry about woman in flood (7)
I believe the answer is:
freshet
'flood' is the definition.
(thesaurus)
'worry about woman' is the wordplay.
'worry' becomes 'fret' (fretting is a kind of worrying).
'about' means one lot of letters goes inside another.
'woman' becomes 'she'.
'fret' going around 'she' is 'FRESHET'.
'in' acts as a link.
(Other definitions for freshet that I've seen before include "Stream or rush of water entering the sea" , "flood" , "He frets over stream running into sea" .)