Worry in West exploded (4)
I believe the answer is:
stew
'worry' is the definition.
(I've seen this in another clue)
'west exploded' is the wordplay.
'exploded' is an anagram indicator.
'west' anagrammed gives 'STEW'.
'in' acts as a link.
(Other definitions for stew that I've seen before include "Casserole" , "Cook by simmering slowly" , "Dish of meat and vegetables cooked slowly in liquid" , "Agitation caused by worry" , "Ragout or burgoo" .)