Worshipped woman with two lives (4)
I believe the answer is:
isis
'worshipped woman' is the definition.
(Egyptian goddess)
'with two lives' is the wordplay.
'two lives' means two replacements for 'lives'.
'with' means one lot of letters go next to another.
'lives' becomes 'is' ('be' can be a synonym of 'live').
'lives' becomes 'is' ('be' can be a synonym of 'live').
'is' next to 'is' is 'ISIS'.
(Other definitions for isis that I've seen before include "Egyptian goddess of nature" , "Wife of Osiris" , "Part of river" , "Oxford's second crew" , "Old Egyptian fertility goddess" .)