Certain trendy writer has flipped desk (10)
I believe the answer is:
inevitable
'certain' is the definition.
(similar in meaning)
'trendy writer has flipped desk' is the wordplay.
'trendy' becomes 'in' ('in' can mean fashionable).
'writer has' becomes 'I've' ('I have' - the person writing has).
'flipped' says the letters should be written in reverse.
'desk' becomes 'table' (a desk is a table for working at).
'ive' reversed gives 'evi'.
'in'+'evi'+'table'='INEVITABLE'
(Other definitions for inevitable that I've seen before include "Unavoidable, fated" , "Certain to happen" , "Inescapable" .)