A little drink at “The Globe” coming back from work (4)
I believe the answer is:
opus
'work' is the definition.
(an opus is an artistic work)
'a little drink at the globe coming back' is the wordplay.
'a little drink' becomes 'sup' (sup can mean a small drink).
'at' is a charade indicator (letters next to each other).
'the globe' becomes 'o' (O resembles a globe).
'coming back' shows that the letters should be reversed in order.
'sup'+'o'='supo'
'supo' written backwards gives 'OPUS'.
'from' is the link.
(Other definitions for opus that I've seen before include "Composer's work" , "Major work" , "Work of 25 perhaps" , "A Latin work" , "Composer's catalogue number" .)