A sphere, for instance, in wrought iron (6)
I believe the answer is:
region
'a sphere' is the definition.
(I know that sphere can be written as region)
'for instance in wrought iron' is the wordplay.
'for instance' becomes 'eg' (short for 'exempli gratia', 'for example' in Latin).
'in' indicates putting letters inside.
'wrought' is an anagram indicator (I've seen this in other clues).
'iron' anagrammed gives 'rion'.
'eg' going into 'rion' is 'REGION'.
(Other definitions for region that I've seen before include "Area, territory" , "Area of country" , "Part of a country" , "Ignore (anag) -- expanse of land" , "Wide area" .)