A vile mixture and bubbly (5)
I believe the answer is:
alive
'bubbly' is the definition.
(I've seen this in another clue)
'a vile mixture' is the wordplay.
'mixture' is an anagram indicator.
'vile' is an anagram of 'live'.
'a'+'live'='ALIVE'
'and' acts as a link.
(Other definitions for alive that I've seen before include "In existence" , "Existing - vigorous" , "Existent" , "operative?" , "answer, as it happens" .)