Aggravated by the necessity to be guided (7)
I believe the answer is:
needled
'aggravated' is the definition.
Although both the answer and definition are past participle verbs, I don't understand how one could define the other.
'by the necessity to be guided' is the wordplay.
'by' means one lot of letters go next to another.
'the necessity' becomes 'need' (synonyms).
'to be guided' becomes 'led' (similar in meaning).
'need'+'led' is 'NEEDLED'.
Can you help me to learn more?
(Other definitions for needled that I've seen before include "Piqued" , "Annoyed - provoked" , "Irritated (sl.)" , "got angry" , "Irked" .)