Drunk, wet, sad, devastated (6)
I believe the answer is:
wasted
'devastated' is the definition.
('wasted' can be a synonym of 'devastated')
'drunk wet sad' is the wordplay.
'drunk' indicates an anagram.
'wet'+'sad'='wetsad'
'wetsad' anagrammed gives 'WASTED'.
(Other definitions for wasted that I've seen before include "three sheets to the wind" , "Not used to good advantage" , "Dissipated; atrophied" , "Having lost weight through illness - dissipated?" , "Used to no purpose" .)