Flipping crazy Fife hooligan headed for nether regions? (6)

I believe the answer is:
damned
'hooligan headed for nether regions?' is the definition.
I can't tell whether this definition defines the answer.
'flipping crazy fife' is the wordplay.
'flipping' shows that the letters should be reversed in order.
'crazy' becomes 'mad' (synonyms).
'fife' becomes 'ned' (I can't explain this - if you can you should believe this answer much more).
'mad' backwards is 'dam'.
'dam'+'ned'='DAMNED'
Can you help me to learn more?
(Other definitions for damned that I've seen before include "Abominable" , "Mad Ned was doomed" , "Cursed" , "Those condemned to eternal punishment" , "Condemned to Hell" .)
