Frank is prepared to do business (4)
I believe the answer is:
open
'frank' is the definition.
(synonyms)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for open that I've seen before include "Liberal" , "hardly high-security" , "'Frank, not secret (4)'" , "yawning" , "Overt" .)