Heartless answer from bank (4)
I believe the answer is:
rely
'bank' is the definition.
(thesaurus)
'heartless answer' is the wordplay.
'heartless' says to hollow out the word (remove centre letters).
'answer' becomes 'reply' ('reply' can be a synonym of 'answer').
'reply' with its centre taken out is 'RELY'.
'from' acts as a link.
(Other definitions for rely that I've seen before include "Be sure" , "Have confidence or faith in" , "Lyre (anag.)" , "Depend (upon)" , "Depend or lean on" .)