High point for the first lady and others (7)
I believe the answer is:
everest
'high point' is the definition.
(I've seen this in another clue)
'first lady and others' is the wordplay.
'first lady' becomes 'eve' (first woman in the Bible).
'and others' becomes 'rest' (I've seen this in other clues).
'eve'+'rest'='EVEREST'
'for the' acts as a link.
(Other definitions for everest that I've seen before include "A high spot" , "Where Hillary was" , "Mount, climbed 1953" , "Huge achievement - highest climb" , "Himalayan mount" .)