Hitch and tie other side (8)
I believe the answer is:
drawback
'hitch' is the definition.
(thesaurus)
'tie other side' is the wordplay.
'tie' becomes 'draw' (synonyms).
'other side' becomes 'back' (the back of something).
'draw'+'back'='DRAWBACK'
'and' is the link.
(Other definitions for drawback that I've seen before include "Hindrance - disadvantage" , "Snag" , "Hindrance - retreat" , "Obstacle" , "Fly in the ointment" .)