Might one seem dog-tired, following the colonel? (6)
I believe the answer is:
collie
'might one seem' is the definition.
I can't tell whether this defines the answer.
'dog-tired following the colonel?' is the wordplay.
'dog tired' becomes 'lie' (I am not sure about this - if you are sure you should believe this answer much more).
'following' is a charade indicator (letters next to each other).
'the colonel?' becomes 'col'.
'lie' after 'col' is 'COLLIE'.
Can you help me to learn more?
(Other definitions for collie that I've seen before include "Working animal" , "Long-haired sheepdog" , "Border dog" , "Sheepdog wth ling nose and shaggy hair" , "Shepherd's dog" .)