One is unusually sound (5)
I believe the answer is:
noise
'sound' is the definition.
(a noise is a sound)
'one is unusually' is the wordplay.
'unusually' indicates anagramming the letters.
'one'+'is'='oneis'
'oneis' with letters rearranged gives 'NOISE'.
(Other definitions for noise that I've seen before include "interference" , "Fuss" , "Confused sounds" , "Loud or disturbing sound" , "Unwelcome sound" .)