Region cares about bad lad (8)
I believe the answer is:
midlands
'region' is the definition.
(I've seen this before)
'cares about bad lad' is the wordplay.
'cares' becomes 'minds' (I've seen this in another clue).
'about' means one lot of letters goes inside another.
'bad' is an anagram indicator.
'lad' with letters rearranged gives 'dla'.
'minds' enclosing 'dla' is 'MIDLANDS'.
(Other definitions for midlands that I've seen before include "SECOND PART OF 20" , "SECOND PART OF 17" , "Region" , "Counties in the centre of Ireland" , "Central area" .)