Second-hand American edition (4)

I believe the answer is:

used

'secondhand' is the definition.
('used' can be a synonym of 'secondhand')

'american edition' is the wordplay.
'american' becomes 'us'.
'edition' becomes 'ed'.
'us'+'ed'='USED'

(Other definitions for used that I've seen before include "Second hand" , "taken advantage of!" , "Old" , "Exploited - not new" , "Accustomed - exploited" .)

I've seen this clue in The Times, The Telegraph and The Guardian.

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