She may be a hit with the FA (5)
I believe the answer is:
faith
'she' is the definition.
'may be a hit with the fa' is the wordplay.
'may be' indicates anagramming the letters.
'with' means one lot of letters go next to another.
'hit' with letters rearranged gives 'ith'.
'ith' after 'fa' is 'FAITH'.
(Other definitions for faith that I've seen before include "Confidence" , "Unshakeable belief" , "It goes with hope and charity" , "'..... will move mountains'" , "Trust in someone" .)