Singers in church or you and me (6)
I believe the answer is:
chorus
'singers' is the definition.
(chorus can mean a group of singers)
'church or you and me' is the wordplay.
'church' becomes 'ch' (common abbreviation).
'you and me' becomes 'us'.
'ch'+'or'+'us'='CHORUS'
'in' is the link.
(Other definitions for chorus that I've seen before include "Group of singers as in musicals" , "Supporting singers and dancers" , "Sing together" , "Speak in unison" , "People singing" .)