Spanish city, sadly looted (6)
I believe the answer is:
toledo
'spanish city' is the definition.
(city in Spain)
'sadly looted' is the wordplay.
'sadly' indicates an anagram.
'looted' is an anagram of 'TOLEDO'.
(Other definitions for toledo that I've seen before include "Sword; city in Ohio" , "Span. sword-making city" , "Looted (anag) - Spanish city" , "Tapering sword" , "Spanish city on R. Tagus" .)