Spiritual liberation Irish see, taken in by simpleton (7)
I believe the answer is:
nirvana
'by simpleton' is the definition.
Although both the answer and definition are singular nouns, I cannot see how one could define the other.
'spiritual liberation irish see taken' is the wordplay.
'spiritual liberation' becomes 'nana' (I can't justify this - if you can you should believe this answer much more).
'irish' becomes 'IR' (abbreviation).
'see' becomes 'v' (short for 'vide', Latin meaning 'see elsewhere').
'taken' indicates putting letters inside.
'ir'+'v'='irv'
'nana' enclosing 'irv' is 'NIRVANA'.
'in' is the link.
Can you help me to learn more?
(Other definitions for nirvana that I've seen before include "religious ecstasy" , "In Buddhist teaching, the place of perfect bliss" , "Eastern place of complete bliss" , "Buddhist enlightened state" , "Buddhist 23" .)