Turned and fled: detectives in pursuit (6)
I believe the answer is:
rancid
'turned' is the definition.
(I've seen this before)
'fled detectives in pursuit' is the wordplay.
I cannot quite see how this works, but
'fled' could be 'ran' (ran away) and 'ran' is located in the answer.
'detectives' could be 'cid' (abbreviation for Criminal Investigation Department) and 'cid' is found within the answer.
No letters remain.
This explanation may well be incorrect...
'and' acts as a link.
Can you help me to learn more?
(Other definitions for rancid that I've seen before include "Unpleasantly stale" , "Sour like stale grease 96)" , "Sour like stale fat" , "(Of butter) gone off" , "Rank, high" .)