Woe is me, sadly: hosting a Republican's tedious (9)
I believe the answer is:
wearisome
'tedious' is the definition.
(I know that tedious can be written as wearisome)
'woe is me sadly hosting a republican's' is the wordplay.
'sadly' is an anagram indicator.
'hosting' is an insertion indicator (inserted letters are welcomed in or hosted).
'republican' becomes 'r' (abbreviation).
'woe'+'is'+'me'='woeisme'
'woeisme' is an anagram of 'weisome'.
'a'+'r'='ar'
'weisome' placed around 'ar' is 'WEARISOME'.
(Other definitions for wearisome that I've seen before include "Boring" , "pestilential" , "Vexatious" , "Tedious, tiring" , "Trying" .)