Great success with hospital information technology (3)
I believe the answer is:
hit
'great success' is the definition.
(I've seen this in another clue)
'with hospital information technology' is the wordplay.
'with' says to put letters next to each other.
'hospital' becomes 'H' (abbreviation for hospital).
'information technology' becomes 'IT' (common abbreviation).
'h' put next to 'it' is 'HIT'.
(Other definitions for hit that I've seen before include "Popular record" , "suit" , "A theatrical success" , "Successful stroke, conspicuous success or connection to a website" , "Badly affected" .)